Aniracetam Benefits and Side Effects

Aniracetam benefits and side effects: A popular Nootropic with mild side effects

Aniracetam is a powerful nootropic with what are considered to be mild side effects. In this article, I will review important benefits of aniracetam benefits and side effects.

Aniracetam (Basic Info)

It’s among the most powerful and popular nootropics belonging to the racetam family ( It doesn’t occur naturally in foods or plants. It’s a purely synthetic cognitive-enhancing compound. Other terms used to refer to this supplement include:

  • (I) N-anisoyl-2-Pyrrolidinone
  • (II) 1-P-anisoyl-2-Pyrrilidinone
  • (III) 1(4-Methoxybenzoyl)-2-Pyrrolidinone
  • (IV) Ro – 13-5057
  • (V) C.A.S. 72432-10-1

Aniracetam Benefits and Side Effects

Aniracetam’s Highlights at a Glance

-Enhances learning of various abstract concepts and literary fluidity

-Improves memory retention

-Boosts creativity

-Improves functioning of the right brain

-Makes vision appear more vivid and sharper

-Enhances mood (anxiolytic)

Why Aniracetam is Popular

It’s popularly claimed to reduce depression and anxiety. It’s also believed to help enhance memory and improve the efficiency of the brain’s ‘AMPA’ receptor sites.

It’s typically taken by a person to stimulate himself/herself mentally, unlike herbal and physical stimulants which are widely regarded as providers of emotional and physical energy. This supplement is sold by various brand names (e.g. Draganon & Memodrin).

It was first synthesized back in the 70s ( and patented by F. Hoffmann – La Roche, a Swiss-based pharmaceutical firm. It was also among the first racetam compounds to be synthesized, coming second right after Piracetam.

That explains why it’s popularly described as Piracetam’s ‘big brother’. Furthermore, it bears a similar pyrrolidone structure to that of Piracetam, among other racetams.

How Aniracetam Differs from the Other Racetams

Aniracetam’s solubility in fat makes it different from other racetams. As such, it’s able to go through blood-brain barriers more easily than Piracetam (water-soluble) ( Its fat-soluble nature enables it to reach the bloodstream way quicker than nearly all other racetam members.

Drug Report And Pills Photo

It’s also considered more potent. But, Aniracetam’s half-life is relatively shorter than that of other similar racetams. One ought to take it more often if he/she is seeking continuous effect.

How Aniracetam Works

Just as it’s with Piracetam, the specific mechanism behind Aniracetam’s nootropic benefits isn’t fully understood. However, that doesn’t imply that nothing is known about it. In fact, it has been intensively researched for more than 40 years now. Quite many interesting findings and facts have emerged, so far.

“Aniracetam works by stimulating certain areas of the cerebral cortex”

Essentially, it works by enhancing blood flow to one’s brain and providing stimulation to certain parts of the cerebral cortex. While Aniracetam and Piracetam bear the same base-structure, the former seems more stimulating and can really amp one’s brain activity quite effectively.

Plenty of research and case studies prove that this supplement has the ability to stimulate various kinds of the brain’s glutamate receptors ( These mainly include ‘AMPA’ and Kainate-receptors. As a result, a stimulatory effect is created in the brain, as such receptors are often excitatory.

Stimulation of the glutamate receptors increases the noradrenaline released by the hippocampal neurons. In turn, that increases activity and transmission of stimulating neurotransmitters found in the brain.

Aniracetam also tends to inhibit GABA-a receptors ( Consequently, sedative effects in one’s brain are reduced while further promoting stimulatory effects in the brain.

Aside from that, Aniracetam has been proven to bring about cholinergic benefits. It improves the signaling of the brain’s acetylcholine receptors. Enhanced activity of such receptors is popularly linked to improved attention, memory, reasoning, and learning.

What Benefits Does Aniracetam Have to Offer?

So far, we’ve discussed the most notable points regarding the functions/effects of this supplement on the brain. Now, we’ll delve into some of the key Aniracetam benefits.

(I) Neuroprotective

Just like most nootropics, Aniracetam is widely considered ‘neuroprotective’. It’s known to alleviate cognitive damage that’s brought about by drug usage, electric shocks, and brain strokes.

(II) Lessen Anxiety & Depression Levels

In animals, Aniracetam (along with its metabolites) has been proven to help reduce the symptoms of depression and anxiety. That’s despite the fact that the compound is said to be stimulatory, not sedative. That effect has also been noted in quite a number of human anecdotes.

(III) Enhance Cognitive Abilities

Most types of ampakine and racetam compounds (including Aniracetam) which stimulate AMPA-receptors have been found to increase production of the Brain-Derived Neurotrophic Factor (abbreviated as BDNF). This factor, then, increases the brain’s plasticity while promoting memory formation, learning, and synaptic signaling.

The most interesting benefits offered by Aniracetam were noted in a certain human study ( Such include the compound’s ability to improve individuals’ overall scores of cognitive tests by up to almost 30%. Rodent studies conclude that this drug is able to continuously promote cognitive abilities.

It has been proven to be more potent, as well, when compared to Piracetam. This racetam’s mechanism has been demonstrated in isolated brain slices and cells, both in various human and animal traits. And, a significant number of research and case studies supports Aniracetam’s claimed attributes as an ideal nootropic cognitive enhancer.

(IV) Possible Solution to Certain Health Conditions

This supplement has been suggested as an option worth considering in addressing certain, major health conditions like fetal alcohol syndrome (, as well as Alzheimer’s and Parkinson’s Disease ( It’s considered a potential treatment solution for memory impairment, among other CNS disorders.

Aniracetam’s Recommended Dosage

The standard dosage recommended for this nootropic ranges from 1,000 mg to 2,000 mg. A typical recommended Aniracetam dosage advises taking two 750-mg doses each day, but at different times. Piracetam, on the other hand, may range as high as over 4800 mg each day.

Although it’s considered up to 5 times more potent, when compared to Piracetam, Aniracetam has a relatively short half-life (often 1-3 hours). That explains why its recommended dosage guidelines encourage taking multiple doses throughout the period cognitive enhancement is needed.

In fact, other recommendations encourage ‘attack-doses’ if you’re taking Aniracetam for the first time to help over-stimulate the neurons. That results in even better synaptic activity.

It might be a viable option for nootropics ( belonging to the racetam class since they’re highly likely to take some time working in the body. Furthermore, they’re deemed safe, even with high dosages. Generally, the large Aniracetam dose recommended would be roughly between two and five times of the normal recommendation.

However, various studies show that Aniracetam works pretty well with low dosages, too. As such, the ideal dosage might be preferably up to individual preferences and experimentation.

Since Aniracetam is fat-soluble, one’s advised to take it with a meal that’s inclusive of some fat. That will help ensure optimal absorption. Besides, it has been proven to increase the amounts of acetylcholine used in the brain.

You should, therefore, supplement it with a top-quality source of choline and choline-rich foods if you’re taking it for acetylcholine synthesis. That will help enhance the benefits offered by Aniracetam while keeping the possible side effects to the minimum.

Aniracetam Side Effects

Aniracetam Side Effects

Nootropics that belong to the racetam class are considered generally safe ( And, although Aniracetam is made synthetically for medicinal purposes, it doesn’t pose any major, known side effects .

Though extremely rare, below are several mild side effects occasionally associated with this supplement:

I. Unrest

II. Headaches

III. Irritability

IV. Insomnia

V. Nausea

VI. Uneasiness

Aniracetam is virtually side effect-free. It has been noted to be extremely well-tolerated by virtually all research animals (mice, rats, dogs, rabbits), and even in cases where high dosages are used. Life-long treatment that comprises the compound has been proven to be unharmful to a human being’s hormones or reproductive system.

It doesn’t show any signs of carcinogenicity or mutagenicity. Even with stupidly high dosages applied to rodents, marmosets, and dogs, racetam compounds barely show any signs/symptoms of acute toxicity.

According to various anecdotal reports collected from blogs and forums, a substantial number of frequent Aniracetam users rarely experience brain fog or headaches. That’s a common side effect of acetylcholine up-regulating nootropics, which is generally explained by poor hydration or inadequate portions of choline in one’s diet.

Aniracetam is naturally stimulatory. It’s capable of interfering with one’s sleep and sedation. For that reason, you shouldn’t take it when bedtime is close. When taken as recommended, it’s considered reasonably safe. It neither causes addiction nor builds up any form of tolerance.

Aniracetam Pros and Cons

Pros: Aniracetam

-Aniracetam enhances memory and alertness

-It raises tolerance levels for stress

-It helps lower depression and anxiety levels

-It motivates and provides increased energy, thus helping with strenuous workouts

Cons: Aniracetam

-An infinitely few users have raised concerns claiming Aniracetam causes depression and anxiety, rather than helping alleviate such states

Legality: Aniracetam

The legality of this supplement for human consumption or research varies from one country to another. It’d only be wise to check your country’s regulations on the same.

Aniracetam has been sold in certain countries, like France, as a prescription medicine. However, the FDA hasn’t approved it for treatment of any health condition or disease.

As a result of that regulatory perspective, Aniracetam is fairly regularly availed for sale on the market but in form of a dietary supplement. Most dietary supplements are sold legally, but without being claimed as a viable solution to any medical condition.

Bottom Line

Piracetol BannerAniracetam’s potential side effects are clearly negligible. In fact, the upsides to this supplement far outweigh the downsides.

It has particularly been studied as a nootropic or cognitive enhancer for a significantly long time, now. And, the scientific literature backing up its claims as performance-enhancer is pretty solid.

Yes, it’s hailed as among the most effective nootropic compounds by most of its users. But, the efficiency of Aniracetam will boil down to your mental ability level, specific needs/preferences, and lifestyle choices.


Bear in mind that the above piece has been crafted as part of our general resources only. We don’t recommend or encourage consumption of drugs which are classified as illegal in your country. More importantly, ensure you consult your doctor prior to modifying your lifestyle healthwise or implementing any changes in your diet.

Benefits of Smart Drugs (Nootropics)

Benefits of smart drugs and their effect on cognitive function

Nootropics represent a multibillion-dollar industry that revolves around the desire or outcome that enhances the way our brain works, its health, and our ability to use it “more better.” Well, just better. However, they do much more than just helping us be better thinkers. In this article, we discuss the benefits of smart drugs.

Benefits of Smart Drugs (Nootropics)

The Sharper Brain

Nootropics are a long list of natural and synthesized compounds that in some way or another impact our brain. They offer a short list of benefits and each nootropic improves the brain a little bit different from the next. The overall benefits include: View More Benefits of Smart Drugs (Nootropics)

Do Nootropic Supplements Work

Do Nootropic supplements work and the benefits you can expect from taking them

When most people hear about nootropics, they can’t help but wonder do these supplements really work. In truth, they do sound like magic potions offered by quacks in the past. However, the science has confirmed that there’s nothing fake about nootropics. In fact, the so-called brain steroids really work! A number of scientific studies have been conducted to show that nootropics have the ability to make the brain run faster, but also to improve memory function and focus. Question is do nootropic supplements work.

The Science behind Nootropics

In order to understand everything about these supplements, you should know how they work. Although each type of nootropics works differently, they all have one thing in common. All of them increase blood flow to the brain. Same as your muscles are capable of lifting bigger weight after you warm up, your brain also will work better when there’s enough blood in it.

Do Nootropic Supplements Work

It’s because nootropics will supply the brain with oxygen and valuable nutrients. Oxygen will provide the brain with energy which it needs in order to work well. All of the other benefits of nootropics are directly related to this. Once the blood is running fast through all the parts of the brain, your focus and attention will get better, as well as your memory. View More Do Nootropic Supplements Work

5 Biggest Benefits of Nootropic Supplements

5 biggest benefits of nootropic supplements and why you may want to try them

Have you ever wished there’s a way to make your brain work better? Since the dawn of time, people have been looking for the magic pill that will make them think faster and be more focused. Believe it or not, such a pill really does exist. These supplements are called Nootropics and it’s not magic that makes them great, but science! In this article I will discuss the 5 biggest benefits of nootropic supplements.

5 Biggest Benefits of Nootropic Supplements- Light Bulk With Brain Image

Nootropics are proven to be great for your brain, affecting its performance in several ways. Here are the top 5 benefits of these supplements, all of which have been confirmed by a number of scientific studies. View More 5 Biggest Benefits of Nootropic Supplements

What are Brain Pills

What are brain pills and how effective are they?

People have always been looking for ways to improve the performances of their brains. It’s not just about being smarter than the others, but people wish to enhance their cognitive performances for a number of other reasons. For example, the faster the brain is working, the easier you’ll learn a new language. In this article we will learn some of the more common benefits of brain pills.

In the past, everything related to the improvement of brain performance had been in the domain of sorcery. Today, science has taken charge! The scientists have designed supplements that will make your brain work faster, enhance your memory, and even make you feel more focused on work. These supplements are called nootropics.

What are Brain Pills - Illustration of the human Brain

If the name of these supplements sounds strange to you, it’s because it comes from the Greek words, “nous” and “trepein”. Actually, the name tells everything about nootropics as those two words literally translate to English as “the mind bender”. Nootropics will bend your mind by making you think more clearly, remember more, and feel better in general. View More What are Brain Pills

Why Students Should Take Nootropic Supplements

If you are struggling with remembering yesterday’s lecture or focusing in school, maybe you should be taking nootropic supplements

Some college lessons seem to exist only to make the lives harder for the students. If a lesson doesn’t have any value for you, surely you won’t find it easy to learn it. Your mind is bound to wander elsewhere, which is why some students decide to cheat, however, there really is no need for cheating. You can learn the lessons by heart with the help of nootropics! In this article I will discuss why students should take nootropic supplements.

Why Students Should Take Nootropic Supplements

Although nootropics can do wonders for your brain, not many students even know what these supplements are. Furthermore, those who do are not sure if nootropics are for them. If you are among those who are having second thoughts about using these “brain supplements”, here are a couple of reasons why you should start taking them right away. View More Why Students Should Take Nootropic Supplements

Benefits and Side Effects of Nootropic Supplements

What are nootropics?

Every now and then, new supplements are introduced in the market that claim to provide you with means to improve your memory and cognitive functions. People tend to be quite wary when it comes to the usage of such supplements as they are apprehensive about the side effects that they may have to face. Nootropics are relatively new supplements which have not been subjected to a great many clinical trials as of yet. However, this does not imply that the supplement has nothing to offer. There are many benefits that you will attain if you make use of them.

Let us take a look at some of the benefits you will get if you use nootropics. We will divide its effects into short and long term benefits to ensure you acquire a better understanding of it.

Long-term benefits

Enhanced neuroplasticity

One of the most appealing benefits that it has to offer that grasps everyone’s attention is that it leads to enhanced neuroplasticity. It improves your memory while at the same time enhancing the performance of the brain.

When a person is young, his brain has the capacity to form new connections between neurons with ease, but this ability tends to witness a decline with age. As you grow old, many neural pathways that are not used by you are blocked, and you no longer have access to the skills that they could have provided you. As a result, you face issues like lower memory capacity and limited learning. Sometimes, memory loss may even result. This issue can be solved by taking nootropics.

Nootropics work on the receptors in the brain, thereby leading to synaptic plasticity. They lead to the formation of new pathways in the brain.


Short-term benefits

There are certain nootropics that should be used for shorter durations or for infrequent dosages. The reason is that prolonged usage can land you in trouble and jeopardize your health. View More Benefits and Side Effects of Nootropic Supplements

The Benefits of Taking Brain Pills

The benefits of taking brain pills to help you improve mental function and retain more of what you are trying to learn.

Bran pills,  also known as nootropics can have many benefits, they are often overlooked and yet for a small investment they can help anyone improve their study skills, eliminate brain fog and excel in their career. Memory loss is something that tends to affect men and women of any age, the brain is just like any other organ in the human body, in order to keep your brain  healthy there are a variety of medicines and supplements to help maintain good cognitive function and overall brain health.

The Benefits of Taking Brain Pills

Not all brain pills (nootropics) are the same, there are natural  substances that can help improve alertness and mental focus,  things like caffeine, Omega 3 fatty acids, and Guarana can all help improve mental focus and alertness.

When choosing a brain pill it is important to decide if you are willing to take a prescription medication, if can get away with a natural brain pill supplement you are better off,  brain pill supplements are much safer, chemical-free, and they do not require a prescription. View More The Benefits of Taking Brain Pills

What Are Smart Drugs?

The short explanation is – Smart Drugs are medications used for improving cognitive functions in healthy human beings. The long explanation is the entirety of this article. Keep reading to know more.

Smart Drugs are also called Nootropics. This word and usage of formulaic synthetic medication to improve function of the ‘brain’, is new to allopathic medicine but the concept of cognitive improvement in normal human beings is not. In fact, cognitive medication has been in use in Chinese and Indian medicines for centuries.

What Are Smart Drugs?
brain in the laboratory

Western medicine is just beginning to take note of the enhancing effects of drugs on cognitive behavior of people. The premise of ‘becoming smarter’ by using medicines does not sit well with the established norms of allopathy, which allow medicines only to ‘cure or alleviate’ an existing medical condition. There is, however, no denying that smart drugs do indeed increase the mental, sensory and perceptive abilities in human beings. View More What Are Smart Drugs?

How Do Nootropic Supplements Work?

A number of nootropic supplements are available in the markets. There are different categories available for the same. Every category has a different mechanism of action, which is why the answer to the question about how nootropic supplements work cannot be straightforward.

In order to attain a better understanding regarding the working of nootropic supplements and their role in enhancing memory and cognitive behavior, you need to acquire a better understanding of the mechanism and neurotransmitters that are involved in the normal functioning of the brain and are responsible for memory and other related functions.

How Do Nootropic Supplements Work?

Neurotransmitters basically refer to chemicals that transmit nerve signals and impulses from one nerve cell to another.

You can think of them as chemical messengers. There are two types of neurotransmitters present: excitatory (which transmit a message) and inhibitory (which are responsible for preventing a message from being received).

The messages received by the neurotransmitters decide the receptors with which the neurotransmitters are supposed to synapse. The neurotransmitters along with the receptors constitute a system for normal functioning.

The nootropic supplements target this system and endeavor to increase its efficiency so as to improve the cognitive function of the brain. Let us not take a look at some of the systems that are targeted by these supplements.


This is the neurotransmitter that can be deemed as the driving force behind the cholinergic system. Acetylcholine plays a pivotal role in many important processes. These include the likes of learning, memory, focus, decision making, and sensory perception.

There are many nootropics supplements that are actually precursors of acetylcholine and serve to enhance the functions that are performed by the neurotransmitter. However, it is often seen that the precursors of acetylcholine are not sufficient to provide you with favorable results, which is why they are often used with agonists to attain a synergistic effect.


Glutamate is the neurotransmitter that is present in the brain in the highest concentration. It has a role to play in maintaining the health of the brain and facilitates processes such as learning and memory. There are a number of nootropic supplements that serve to stimulate the receptors of this neurotransmitter.

Nootropic supplement pills

Dopamine and serotonin

These two neurotransmitters are usually not the primary targets of nootropics supplements as they mainly deal with feelings of pleasure and happiness. However, they do have a certain effect on the overall effectiveness of the supplements.

Supplements that stimulate the production of dopamine can be addictive, which is why it is better to refrain from making use of them on a daily basis.

The basic effect

If you are looking to understand how the nootropic supplements work, you should endeavor to find out more about these five neurotransmitters, namely acetylcholine, glutamate, GABA, dopamine, and serotonin. They have a huge role to play in the mechanism via which nootropics work.

Neurotransmitters are chemicals that form the source of communication between the different parts of the brain. Due to these chemicals, your brain is able to perform various cognitive activities.

These include the likes of your learning process, memorizing things, processing, calculating, reasoning, imagination, creativity, focus, feeling and perception. The synapses formed via the neurons due to these chemicals are responsible for all these functions. The nootropic supplements basically serve to optimize these connections, thereby ensuring that the cognitive abilities of the person are improved.

There remains a bit of a controversy surrounding these supplements as studies continue to be conducted with regards to their efficacy. There are many supplements whose exact mechanism of action is not known to date.


So do nootropic supplements work? The answer is yes, it all depends on what you are trying to achieve, believe it or not there are a variety of nootropic supplements that work differently, for example, Nootropics like NooCube would be more suited for students or people suffering from memory retention problems. If you are into sports or bodybuilding there are actually Nootropics such as Muscletronic which helps improve mental focus, strength, and motivation is essential for better athletic performance and bodybuilding.